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pentobarbital will lessen the extent or effect of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Double brexpiprazole dose over one-2 weeks if administered with a powerful CYP3A4 inducer.Watch Carefully (2)pentobarbital will reduce the extent or effect of buprenorphine, long-performin